P362 Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes

Objective: To diagnose and lateralise temporal lobe epilepsy (TLE) by building a classification system that uses directed functional connectivity patterns estimated during EEG periods without visible pathological activity. Methods: Resting-state high-density EEG recording data from 20 left TLE patients, 20 right TLE patients and 35 healthy controls was used. Epochs without interictal spikes were selected. The cortical source activity was obtained for 82 regions of interest and whole-brain directed functional connectivity was estimated in the theta, alpha and beta frequency bands. These connectivity values were then used to build a classification system based on two two-class Random Forests classifiers: TLE vs healthy controls and left vs right TLE. Feature selection and classifier training were done in a leave-one-out procedure to compute the mean classification accuracy. Results: The diagnosis and lateralization classifiers achieved a high accuracy (90.7% and 90.0% respectively), sensitivity (95.0% and 90.0% respectively) and specificity (85.7% and 90.0% respectively). The most important features for diagnosis were the outflows from left and right medial temporal lobe, and for lateralization the right anterior cingulate cortex. The interaction between features was important to achieve correct classification

Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

Onderwijsontwikkelingen

Afdeling Theoretische, cultuur- en onderwijssociologie. Centrum voor Onderwijssociologie (COS)status: publishe

Design of a Haptic Language for Gestural Control of Smart Lights

International audienceUbiquitous haptics draws from ubiquitous computing and aims to integrate haptics in everyday life to render interaction with technology seamless and intuitive. We describe an explorative design process that takes ubiquitous haptics as a starting point and aims to discover opportunities for haptics in a near future in which smart objects and haptic feedback are omnipresent. Through hands-on experimentation and brainstorming, we conceived a concept for the use of haptic feedback as part of a gestural language for interactions with connected devices, and more specifically with smart lights. The concept was developed and validated by exploring usage scenarios and experimenting with low-fidelity Wizard-of-Oz prototypes and high-fidelity prototype in virtual reality. This process led to the design of an intuitive and seamless user experience for smart lighting control based on a synergy between gestures and haptic feedback

Le développement de l'éducation

Afdeling Theoretische, cultuur- en onderwijssociologie. Centrum voor Onderwijssociologie (COS)nrpages: 127status: publishe

Le développement de l'éducation

Afdeling Theoretische, cultuur- en onderwijssociologie. Centrum voor Onderwijssociologie (COS)nrpages: 127status: publishe

The development of education

Afdeling Theoretische, cultuur- en onderwijssociologie. Centrum voor Onderwijssociologie (COS)status: publishe

Nationaal rapport van de UNESCO

Afdeling Theoretische, cultuur- en onderwijssociologie.status: publishe

Assessing the operation of typical Dutch distribution systems with large penetration of low-carbon energy technologies

Currently, the majority of the available test feeder models are based on the North American type of distribution systems, leaving an absence of representative feeder models for the European (and Dutch) types of distribution systems. Therefore, a standardized set of power flow models for typical Dutch LV distribution networks is developed using real networks and operational data provided by a Dutch DSO. These network models are used to assess if typical Dutch LV distribution networks are ready to operate with large penetration of low-carbon energy technologies (e.g. PV systems, electric heat pumps, EVs). According to the obtained results, simulations of all the modelled networks showed the same behaviour for the power flow at the head of the distribution system and the voltage magnitude level. The changes in voltage magnitude however is dependent on the size of the network, resulting in larger changes in the larger networks. While the voltage magnitude level of the smaller networks stays within the ± 10% range, the larger networks encounter voltage magnitude violations. Thus, it can be concluded that the larger networks are not ready (under the current conditions) for large penetrations of low-carbon energy technologies, while the smaller networks appear to be ready